Better patient compliance due to lesser pill load & increased adherence to therapy
PIOGLITAZONE
- Disposal and decreased haptic glucose output
- Decreases insulin resistance in the periphery and in the liver resulting in increased insulin dependant glucose.
GLIMEPIRIDE
- No accumulation of the during in patient.
- For non insulin dependent diabetes mellitus.
- Increases insulin secretion in response to glucose 2 causes no weight gain
METFORMIN
- Metformin provides additional benefits counteracting several cardiovascular risk factors.
- Improves peripheral & hepatic sensitivity to insulin.
- Significant reduction in GI side effects.